Histological analysis of chronically stimulated human vagus nerves is lacki
ng in the literature. In this study, we describe the first microscopic find
ings in a chronically stimulated left vagus nerve from a pediatric patient.
Our results show many histological changes in and around the stimulated ne
rve with severe demyelination. Further long-term clinical and postmortem ex
aminations of chronically stimulated vagus nerves in both children and adul
ts are needed to ascertain whether prolonged exposure to electrical current
can cause clinical dysfunction of this nerve. Copyright (C) 2001 S. Karger
AG, Basel.