Painful multifocal arthritis: Therapy with rhenium 186 hydroxyethylidenediphosphonate (Re-186 HEDP) after failed treatment with medication - Initial results of a prospective study

Authors
Palmedo, H Rockstroh, JK Bangard, M Schliefer, K Risse, J Menzel, C Biersack, HJ
Citation
H. Palmedo et al., Painful multifocal arthritis: Therapy with rhenium 186 hydroxyethylidenediphosphonate (Re-186 HEDP) after failed treatment with medication - Initial results of a prospective study, RADIOLOGY, 221(1), 2001, pp. 256-260
Citations number
24
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Medical Research Diagnosis & Treatment
Journal title
RADIOLOGY
ISSN journal
00338419 → ACNP
Volume
221
Issue
1
Year of publication
2001
Pages
256 - 260
Database
ISI
SICI code
0033-8419(200110)221:1<256:PMATWR>2.0.ZU;2-X
Abstract
Eight patients (77 joints) with polyarthritis were treated systemically wit h 570 MBq (15.4 mCi) of rhenium 186 (Re-186) hydroxyethylidenediphosphonate (HEDP). Pain and disease activity were assessed monthly. In six (75%) of e ight patients, a single injection of Re-186 HEDP led to an improvement in d isease activity. Systemic low-dose treatment with Re-186 HEDP can reduce pa in and disease activity in patients with polyarthritis.