New route to vicasol, a water-soluble form of vitamin K-3

Authors
Matveev, KI Odyakov, VF Zhizhina, EG
Citation
Ki. Matveev et al., New route to vicasol, a water-soluble form of vitamin K-3, RUS J AP CH, 74(3), 2001, pp. 469-472
Citations number
29
Categorie Soggetti
Chemistry
Journal title
RUSSIAN JOURNAL OF APPLIED CHEMISTRY
ISSN journal
10704272 → ACNP
Volume
74
Issue
3
Year of publication
2001
Pages
469 - 472
Database
ISI
SICI code
1070-4272(200103)74:3<469:NRTVAW>2.0.ZU;2-M
Abstract
A procedure was suggested for preparing vicasol in an approximately 85% yie ld in a two-phase system consisting of concentrated (similar to5-6 M) aqueo us solution of NaHSO3 and a solution of 2-methyl-1,4-naphthoquinone in an i ncombustible organic solvent (e.g., chloroform or trichloroethylene).