Penicillin detection by means of field-effect based sensors: EnFET, capacitive EIS sensor or LAPS?

Three types of semiconductor field-effect penicillin sensors, enzyme field- effect transistors (EnFETs), capacitive electrolyte-insulator-semiconductor (EIS) sensors and light-addressable potentiometric sensors (LAPS) have bee n developed and tested for the penicillin detection. For all sensor types t he enzyme penicillinase was adsorptively immobilised directly onto a pH-sen sitive Ta2O5 surface. Some basic parameters of these sensors (e.g. sensitiv ity, linear range, detection limit, response time, hysteresis and life time ) are investigated and their performances with regard to the respective mea surement set-up as well as the sensor configuration are compared. (C) 2001 Elsevier Science B.V. All rights reserved.