Facile synthesis of (+)-alpha-allokainic acid via Pd-catalyzed hydrogenolysis of allyl acetate derived from trans-4-hydroxy-L-proline

Authors
Ma, DW Wu, WG Deng, P
Citation
Dw. Ma et al., Facile synthesis of (+)-alpha-allokainic acid via Pd-catalyzed hydrogenolysis of allyl acetate derived from trans-4-hydroxy-L-proline, TETRAHEDR L, 42(39), 2001, pp. 6929-6931
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
39
Year of publication
2001
Pages
6929 - 6931
Database
ISI
SICI code
0040-4039(20010924)42:39<6929:FSO(AV>2.0.ZU;2-7
Abstract
Pd(PPh3)(4)/PPh3-catalyzed hydrogenolysis of 3a derived from trans-4-hydrox y-L-proline using ammonium formate as a hydride reagent, provides olefin 4 as a major product, which is hydrolyzed to give (+)-alpha -allokainic acid. (C) 2001 Elsevier Science Ltd. All rights reserved.