Stereoselective synthesis of gem-dimethyl-5,5-pyrrolidine-trans-lactam (5-oxo-hexahydropyrrolo[3,2-b]pyrrole)

Authors
Borthwick, AD Davies, DE Exall, AM Pennell, AMK Richards, JJ
Citation
Ad. Borthwick et al., Stereoselective synthesis of gem-dimethyl-5,5-pyrrolidine-trans-lactam (5-oxo-hexahydropyrrolo[3,2-b]pyrrole), TETRAHEDR L, 42(39), 2001, pp. 6933-6935
Citations number
9
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
39
Year of publication
2001
Pages
6933 - 6935
Database
ISI
SICI code
0040-4039(20010924)42:39<6933:SSOG(>2.0.ZU;2-H
Abstract
The gem-dimethyl-trans-lactam 6 could be prepared by alkylation of the beta -methyl isomer 7 but not by alkylation of the alpha -isomer 5. (C) 2001 El sevier Science Ltd. All rights reserved.