An efficient chemo and regioselective oxidative nuclear bromination of activated aromatic compounds using lithium bromide and ceric ammonium nitrate

Authors
Roy, SC Guin, C Rana, KK Maiti, G
Citation
Sc. Roy et al., An efficient chemo and regioselective oxidative nuclear bromination of activated aromatic compounds using lithium bromide and ceric ammonium nitrate, TETRAHEDR L, 42(39), 2001, pp. 6941-6942
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
39
Year of publication
2001
Pages
6941 - 6942
Database
ISI
SICI code
0040-4039(20010924)42:39<6941:AECARO>2.0.ZU;2-2
Abstract
A mild, efficient and highly chemo- and regioselective method for the bromi nation of electron rich aromatic molecules has been developed by electrophi lic substitution of Br+, which was generated in situ from LiBr using ceric ammonium nitrate as the oxidant. Free aromatic amines remained unaffected u nder the reaction conditions. (C) 2001 Elsevier Science Ltd. All rights res erved.