Persistent hyperplastic primary vitreous (PHPV) syndrome associated with ei
ther severe ocular complications or multiple ocular lesions was diagnosed i
n three young dogs, a Samoyed, a Spanish Pachon, and a mixed breed dog. Due
to opacification of the anterior ocular structures, B-mode and color-flow
Doppler ultrasonography were performed to aid diagnosis. The Samoyed presen
ted with unilateral hyphema; the Spanish Pachon presented with unilateral s
econdary glaucoma associated with uveitis and hyphema OD and leucocoria OU;
and the mixed breed presented with bilateral leucocoria. B-mode ultrasonog
raphy of the Samoyed revealed a subcapsular cataract and a hyperechoic tubu
lar structure attached from the optic disk to the posterior lens capsule. I
n the Spanish Pachon B-mode ultrasonography of the right eye indicated micr
ophakia, cataract formation, and a retrolental mass with a thin hyperechoic
strand stretching from the optic disk to the posterior lens; and for the r
ight eye cataract formation, PHPV, retinal detachment, and vitreous hemorrh
age. In the mixed breed dog, B-mode ultrasonography of both eyes indicated
microphthalmia, retrolental mass, and hyperechoic lenses. By color-flow Dop
pler imaging, blood flow was present in the retrolental mass of the right e
ye suggesting a persistent hyaloid artery.