Overview of circadian rhythms

Citation
Mh. Vitaterna et al., Overview of circadian rhythms, ALCOHOL R H, 25(2), 2001, pp. 85
Citations number
14
Categorie Soggetti
Public Health & Health Care Science
Journal title
ALCOHOL RESEARCH & HEALTH
ISSN journal
15357414 → ACNP
Volume
25
Issue
2
Year of publication
2001
Database
ISI
SICI code
Abstract
The daily light-dark cycle governs rhythmic changes in the behavior and/or physiology of most species. Studies have found that these changes are gover ned by a biological clock, which in mammals is located in two brain areas c alled the suprachiasmatic nuclei. The circadian cycles established by this clock occur throughout nature and have a period of approximately 24 hours. In addition, these circadian cycles can be synchronized to external time si gnals but also can persist in the absence of such signals. Studies have fou nd that the internal clock consists of an array of genes and the protein pr oducts they encode, which regulate various physiological processes througho ut the body. Disruptions of the biological rhythms can impair the health an d well-being of the organism.