Disease management (DM) is becoming an increasingly important tool for use
in end-stage renal disease (ESRD). The goal of a DM program is to offer a c
ontinuum of care that uses guidelines and case management protocols to prev
ent acute care episodes, achieve improved outcomes and reduce health care c
osts. This article reviews the theory behind DM, describes key components o
f DM programs and explains the financial incentives for DM in ESRD. Of key
importance in the increasing role of DM for ESRD has been the development o
f nationally recognized guidelines, the effects of which are now beginning
to emerge. At the same time, recent studies have identified targeted opport
unities for DM programs to improve outcomes and costs, including anemia man
agement, dialysis dose, and vascular access. DM, through the use of guideli
nes and targeted toward these and other areas, has the potential to signifi
cantly impact the quality of care provided to ESRD patients. Copyright (C)
2001 S. Karger AG, Basel.