Incorporation of a novel nucleobase allows stable oligonucleotide-directedtriple helix formation at the target sequence containing a purine center dot pyrimidine interruption

Authors
Guianvarc'h, D Benhida, R Fourrey, JL Maurisse, R Sun, JS
Citation
D. Guianvarc'H et al., Incorporation of a novel nucleobase allows stable oligonucleotide-directedtriple helix formation at the target sequence containing a purine center dot pyrimidine interruption, CHEM COMMUN, (18), 2001, pp. 1814-1815
Citations number
26
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
18
Year of publication
2001
Pages
1814 - 1815
Database
ISI
SICI code
1359-7345(20010921):18<1814:IOANNA>2.0.ZU;2-B
Abstract
Thermal denaturation experiments have established that an oligonucleotide i ncorporating the artificial nucleobase S, does form a stable triplex with a double stranded DNA which exhibits a pyrimidine interruption within the ol igopurine sequence.