Dodeca(carboranyl)-substituted closomers: toward unimolecular nanoparticles as delivery vehicles for BNCT

Authors
Thomas, J Hawthorne, MF
Citation
J. Thomas et Mf. Hawthorne, Dodeca(carboranyl)-substituted closomers: toward unimolecular nanoparticles as delivery vehicles for BNCT, CHEM COMMUN, (18), 2001, pp. 1884-1885
Citations number
14
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
18
Year of publication
2001
Pages
1884 - 1885
Database
ISI
SICI code
1359-7345(20010921):18<1884:DCTUN>2.0.ZU;2-F
Abstract
The syntheses of the dodeca(carboranyl)-substituted closomers, dodeca[7-(2- methyl-1,2-dicarba-closo-dodecaboran-1-yl)heptanoate]-closo-dodecaborate(2- ) and dodeca[7-(8-methyl-7,8-dicarba-nido-dodecaboran-7-yl)heptanoate]-clos o-dodecaborate(14-) are reported. These boron-rich, unimolecular nanosphere s possess great potential for future use as drug-delivery platforms for bor on neutron capture therapy (BNCT).