Hg. Koebe et al., ARTIFICIAL LIVER - IMMOBILISATIONS TECHNI QUE REPRESENTING A NEW METHOD OF CULTURE OF (HUMAN) HEPATOCYTES, Die medizinische Welt, 45(10), 1994, pp. 415-418
Collagen gel immobilisation represents a new cell culture technique, i
n which hepatocellular function and morphological integrity can be pre
served over long term periods under standardised conditions. An easy a
pplication method, the cryopreservability of cell cultures and a high
resistance of culture systems against shear forces of fluids in a dyna
mic application (bioreactor) let this technique be recommended for the
construction of hybrid organ systems, esp. with respect to industrial
production.