On the validity of the two-cells model in the analysis of passive electrical properties of gap-junction connected cells

Authors
Andreu, E Fernandez, E Louis, E Ortega, G Sanchez-Andres, JV
Citation
E. Andreu et al., On the validity of the two-cells model in the analysis of passive electrical properties of gap-junction connected cells, EUR BIOPHYS, 30(5), 2001, pp. 374-377
Citations number
17
Categorie Soggetti
Biochemistry & Biophysics
Journal title
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
ISSN journal
01757571 → ACNP
Volume
30
Issue
5
Year of publication
2001
Pages
374 - 377
Database
ISI
SICI code
0175-7571(200109)30:5<374:OTVOTT>2.0.ZU;2-W
Abstract
It is a rather extended practice to derive electrophysiological data, (memb rane and contact conductances) from experimental data for gap-junction tiss ues assuming that electrical connections are reduced to cell pairs. It is h ere shown that, if the length constant is sufficiently large, the mentioned procedure can lead to qualitatively incorrect results.