Nitric oxide metabolites in gnotobiotic piglets orally infected with Salmonella enterica serovar typhimurium

Authors
Trebichavsky, I Zidek, Z Frankova, D Zahradnickova, M Splichal, I
Citation
I. Trebichavsky et al., Nitric oxide metabolites in gnotobiotic piglets orally infected with Salmonella enterica serovar typhimurium, FOL MICROB, 46(4), 2001, pp. 353-358
Citations number
35
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
FOLIA MICROBIOLOGICA
ISSN journal
00155632 → ACNP
Volume
46
Issue
4
Year of publication
2001
Pages
353 - 358
Database
ISI
SICI code
0015-5632(2001)46:4<353:NOMIGP>2.0.ZU;2-3
Abstract
Reactive NO metabolites play a distinct role in the control of Salmonella e nterica serovar Typhimurium (ST, a facultative intracellular pathogen) in s usceptible host. A significant increase of nitrite and/or nitrate plasma le vels, 3-nitro- tyrosine expression and pathological changes in mesenteric l ymph nodes have been observed in gnotobiotic piglets orally infected for 1 d with a virulent strain of ST but not in pip-lets infected with a rough mu tant of ST.