NEW ANTI-HIV-1, ANTIMALARIAL, AND ANTIFUNGAL COMPOUNDS FROM TERMINALIA-BELLERICA

Authors
VALSARAJ R PUSHPANGADAN P SMITT UW ADSERSEN A CHRISTENSEN SB SITTIE A NYMAN U NIELSEN C OLSEN CE
Citation
R. Valsaraj et al., NEW ANTI-HIV-1, ANTIMALARIAL, AND ANTIFUNGAL COMPOUNDS FROM TERMINALIA-BELLERICA, Journal of natural products, 60(7), 1997, pp. 739-742
Citations number
24
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy","Chemistry Medicinal
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
60
Issue
7
Year of publication
1997
Pages
739 - 742
Database
ISI
SICI code
0163-3864(1997)60:7<739:NAAAAC>2.0.ZU;2-K
Abstract
A bioactivity-guided fractionation of an extract of Terminalia belleri ca fruit rind led to the isolation of two new lignans named termiligna n (1) and thannilignan (2), together with 7-hydroxy-3',4'-(methylenedi oxy)flavan (3) and anolignan B (4). All four compounds possessed demon strable anti-HIV-1, antimalarial, and antifungal activity in vitro.