Genetic protection from the inflammatory disease type 1 diabetes in humansand animal models

Authors
Todd, JA Wicker, LS
Citation
Ja. Todd et Ls. Wicker, Genetic protection from the inflammatory disease type 1 diabetes in humansand animal models, IMMUNITY, 15(3), 2001, pp. 387-395
Citations number
75
Categorie Soggetti
Immunology
Journal title
IMMUNITY
ISSN journal
10747613 → ACNP
Volume
15
Issue
3
Year of publication
2001
Pages
387 - 395
Database
ISI
SICI code
1074-7613(200109)15:3<387:GPFTID>2.0.ZU;2-I
Abstract
Populations of humans and mice contain alleles at many loci that protect fr om immune-mediated diseases. Identification of these alleles, some which ar e likely to function in immune recognition, tolerance, and regulation, will facilitate the development of diagnostics as well as therapeutics that alt er disease progression.