Body mass index (BMI) is used as a reference for weight control programs in
the general population and in morbidity and mortality studies in diabetes
patients. However, the implications of BMI in chronic hemodialysis patients
is unclear. We studied the BMI of chronic hemodialysis patients, focusing
on problems encountered during outpatient hemodialysis therapy and on 2-yea
r mortality. Outpatients with chronic hemodialysis (n = 258; 144 men, 114 w
omen) were divided into four groups: (i) patients with stable hemodialysis;
(ii) patients with marked hypotension requiring catecholamine infusion dur
ing hemodialysis; (iii) patients with excessive interdialysis weight gain r
equiring occasional additional hemodialysis; and (iv) patients with trouble
some hemodialysis due to other causes. The statistical differences between
the average BMI among these groups were evaluated, and were subdivided into
sex, age and the duration of hemodialysis history. The 2-year mortality ra
tes of these patients were also studied according to their BMI. In patients
under 60 years of age, those with excessive interdialysis weight gain had
statistically larger BMI (23.2; n = 35) compared to patients with good hemo
dialysis control (20.1; n = 178), regardless of gender and hemodialysis his
tory. The mortality rate was at a minimum at approximately 20 BMI in patien
ts under 60 years of age. However, lower BMI was associated with a greater
mortality rate in patients 60 years or over. For chronic hemodialysis patie
nts, the BMI associated with stable hemodialysis and minimum mortality is a
pproximately 20, in those under 60 years of age. The BMI of aged hemodialys
is patients should be considered separately in morbidity and mortality stud
ies.