First molecular characterization of HIV-1 Tunisian strains

Authors
Ben Halima, M Pasquier, C Slim, A Ben Chaabane, T Arrouji, Z Puel, J Ben Redjeb, S Izopet, J
Citation
M. Ben Halima et al., First molecular characterization of HIV-1 Tunisian strains, J ACQ IMM D, 28(1), 2001, pp. 94-96
Citations number
6
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
ISSN journal
15254135 → ACNP
Volume
28
Issue
1
Year of publication
2001
Pages
94 - 96
Database
ISI
SICI code
1525-4135(20010901)28:1<94:FMCOHT>2.0.ZU;2-6
Abstract
In order to identify HIV-1 subtypes circulating in Tunisia, blood specimens from 25 HIV-1 rifected Tunisian patients were collected. Proviral HIV-1 DN A was genotyped by sequence analysis of the C2-V3 env, region. HIV-1 subtyp es were determined in 21 DNA sequences: 20 were of subtype B and one was a circulating recombinant form (CRF02 AG). Subtype B largely dominates the epidemiology of HIV-1 infection in Tunisia, suggesting the probable imported origin of HIV-1 infection, but further st udies are needed to investigate the potential diversification of HIV-1 isol ates in Tunisia.