The essential oils obtained from the aerial parts of Origanum scabrum and O
rigaum microphyllum, both endemic species in Greece, were analyzed by means
of GC and GC-MS. Forty-eight constituents were identified, representing 98
.59 and 98.66% of the oils, respectively. Carvacrol, terpinen-4-ol, linaloo
l, sabinene, alpha -terpinene, and gamma -terpinene were found as the major
components. Furthermore, both samples exhibited a very interesting antimic
robial profile after they were tested against six Gram-negative and -positi
ve bacteria and three pathogenic fungi.