Chromatographic determination of polyiodohalides of organic nitrogen bases

The following biologically active polyiodohalides of organic nitrogen bases were synthesized and studied: trimethylbenzylammonium, triethylbenzylammon ium, and N-cetylpyridinium diiodochlorides; tetramethylammonium, tetrabutyl ammonium, and N-cetylpyridinium diiodobromides; and butylcholinium triiodid e. A method for the identification of the above compounds was proposed base d on the dependence of their thin-layer chromatographic mobility and IR, UV , and NMR spectrometric properties and on the nature of the organic cation and the structure of the polyiodide anion. Reversed-phase high-performance liquid chromatography in a I : I methanol-water mixture (pH 6.86) was used for determining the compounds under study. The developed procedure is chara cterized by high sensitivity (0.09-0.51 mug) at RSD of no worse than 10%.