The following biologically active polyiodohalides of organic nitrogen bases
were synthesized and studied: trimethylbenzylammonium, triethylbenzylammon
ium, and N-cetylpyridinium diiodochlorides; tetramethylammonium, tetrabutyl
ammonium, and N-cetylpyridinium diiodobromides; and butylcholinium triiodid
e. A method for the identification of the above compounds was proposed base
d on the dependence of their thin-layer chromatographic mobility and IR, UV
, and NMR spectrometric properties and on the nature of the organic cation
and the structure of the polyiodide anion. Reversed-phase high-performance
liquid chromatography in a I : I methanol-water mixture (pH 6.86) was used
for determining the compounds under study. The developed procedure is chara
cterized by high sensitivity (0.09-0.51 mug) at RSD of no worse than 10%.