Ma. Thomas et al., Volume-localized two-dimensional correlated magnetic resonance spectroscopy of human breast cancer, J MAGN R I, 14(2), 2001, pp. 181-186
A localized 2D correlation spectroscopic sequence (L-COSY) was implemented
and applied in human breast cancer in vivo to evaluate the water to fat (bo
th saturated and unsaturated) ratios and also to identify choline. Being in
agreement with the conventional 1D magnetic resonance spectroscopy (MRS) r
esults, elevated water to lipids ratios were found in breast cancers and ch
oline was observed only in a few cancer patients. (C) 2001 Wiley-Liss, Inc.