MRI: A role in clinical trials

The diagnosis and treatment of breast cancer has evolved significantly over the last 20 years. Breast-conserving therapy Is replacing the Halstedian c oncept of "en bloc" resection. Difficulties In detection, pre- and postoper ative planning and follow up continue to challenge the clinician. Women at high risk present a significant clinical dilemma. MRI technology in many of these areas is providing more Information about detection, tumor size, ext ent, and response to treatment. The careful and thoughtful inclusion of MRI in clinical trials may help continue the advancement of breast cancer care . (C) 2001 Wiley-Liss, Inc.