The injection of boluses of carbon dioxide (CO2) during T1-weighted magneti
c resonance angiography (MRA) resulted in sharp depiction of the vascular l
umen during the performance of in vitro and in vivo animal experiments. We
propose the use of the low-cost, relatively safe CO2 as a negative contrast
agent for MIRA and speculate on its use in future interventional MRA. (C)
2000 Wiley-Liss, Inc.