A single dose of nebulized budesonide decreases exhaled nitric oxide in children with acute asthma

Authors
Tsai, YG Lee, MY Yang, KD Chu, DM Yuh, YS Hung, CH
Citation
Yg. Tsai et al., A single dose of nebulized budesonide decreases exhaled nitric oxide in children with acute asthma, J PEDIAT, 139(3), 2001, pp. 433-437
Citations number
17
Categorie Soggetti
Pediatrics,"Medical Research General Topics
Journal title
JOURNAL OF PEDIATRICS
ISSN journal
00223476 → ACNP
Volume
139
Issue
3
Year of publication
2001
Pages
433 - 437
Database
ISI
SICI code
0022-3476(200109)139:3<433:ASDONB>2.0.ZU;2-Q
Abstract
This study was conducted to investigate whether a single dose of nebulized budesonide effectively decreased airway inflammation as demonstrated by exh aled nitric oxide (eNO) levels. A single dose of nebulized budesonide, but not nebulized terbutaline, rapidly decreased eNO levels in 6 hours. The dec rease in eNO levels induced by nebulized budesonide was correlated to an in crease in peak expiratory flow rate.