Yg. Tsai et al., A single dose of nebulized budesonide decreases exhaled nitric oxide in children with acute asthma, J PEDIAT, 139(3), 2001, pp. 433-437
This study was conducted to investigate whether a single dose of nebulized
budesonide effectively decreased airway inflammation as demonstrated by exh
aled nitric oxide (eNO) levels. A single dose of nebulized budesonide, but
not nebulized terbutaline, rapidly decreased eNO levels in 6 hours. The dec
rease in eNO levels induced by nebulized budesonide was correlated to an in
crease in peak expiratory flow rate.