THE INFLUENCE OF HIPPOCAMPECTOMY ON ELABO RATION AND RECOVERY OF TIMECONDITIONED REFLEX IN RATS

Citation
Mg. Vodolazhskaya, THE INFLUENCE OF HIPPOCAMPECTOMY ON ELABO RATION AND RECOVERY OF TIMECONDITIONED REFLEX IN RATS, Zurnal vyssej nervnoj deatelnosti im. I.P. Pavlova, 47(3), 1997, pp. 480-486
Citations number
16
Categorie Soggetti
Physiology,Neurosciences
ISSN journal
00444677
Volume
47
Issue
3
Year of publication
1997
Pages
480 - 486
Database
ISI
SICI code
0044-4677(1997)47:3<480:TIOHOE>2.0.ZU;2-4
Abstract
The dynamics of time conditioning was studied before and after electro lytic lesions of the dorsal hippocampus in rats, Hippocampectomy distu rbed the recovery of time conditioned reflex which was consolidated be fore surgery, The change depended on the extent of hippocampal lesion. In rats after the limited hippocampectomy the conditioned reflex reco vered faster than in sham-operated animals. However. after more extens ive lesions the process of conditioning recovery was delayed, In hippo campectomized animals without previous training the time conditioned r eflex was not formed irrespective of the volume of brain lesion, Injec tion of amphetamine (0.05 mg/kg) was ineffective in this case.