Reversible agranulocytosis associated with oral terbinafine in a pediatricpatient

Authors
Aguilar, C Mueller, KK
Citation
C. Aguilar et Kk. Mueller, Reversible agranulocytosis associated with oral terbinafine in a pediatricpatient, J AM ACAD D, 45(4), 2001, pp. 632-634
Citations number
10
Categorie Soggetti
Dermatology,"da verificare
Journal title
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
ISSN journal
01909622 → ACNP
Volume
45
Issue
4
Year of publication
2001
Pages
632 - 634
Database
ISI
SICI code
0190-9622(200110)45:4<632:RAAWOT>2.0.ZU;2-R
Abstract
We report a case of terbinafine-induced agranulocytosis in a pediatric pati ent. This effect was noted 4 weeks after starting terbinafine and resolved within I week without the institution of therapy with granulocyte colony-st imulating factor, a course similar to reports in adults. With the incidence of severe side effects still unclear in children, this case argues for con tinued blood surveillance during courses of terbinafine and for the confirm ation of infection before initiation of the drug.