Endoscopic cryosurgery of the thyroid and parathyroid

In this study we looked at the efficacy of cryosurgery for thyroid and para thyroid tissue ablation in the porcine model. An endoscopic neck approach w as successfully used in six 25 kg pigs. T4, free T4 and calcium serum level s were measured pre- and post-operatively. Gross and histologic examination of the glands and surrounding tissue were performed on postoperative Day 4 0. Postoperative T4, free T4 and calcium levels were not significantly diff erent from preoperative values. Gross examination of the thyroid showed sca r tissue in the region that underwent cryosurgery. Parathyroid that was fro zen was replaced by scar tissue. Histologic examination of the glands confi rmed the gross findings. Trachea, vagus nerve and carotid artery were also resected, and no changes were noted on histological examination. There was no damage to the surrounding tissues after cryosurgery. Directed cryosurger y of the thyroid and parathyroid is safe and feasible in this model.