We perform Monte Carlo simulations of synthetic EMSS cluster samples, to qu
antify the systematic errors and the statistical uncertainties on the estim
ate of Omega (0) derived from fits to the cluster number density evolution
and to the X-ray temperature distribution up to z=0.83. We identify the sca
tter around the relation between cluster X-ray luminosity and temperature t
o be a source of systematic error, of the order of Delta (syst)Omega (0) =
0.09, if not properly taken into account in the modelling. After correcting
for this bias, our best Omega (0) is 0.66. The uncertainties on the shape
and normalization of the power spectrum of matter fluctuations imply relati
vely large uncertainties on this estimate of Omega (0), of the order of Del
ta (stat)Omega (0) = 0.1 at the 1 sigma level. On the other hand, the stati
stical uncertainties due to the finite size of the high-redshift sample are
twice as small. Therefore, what is needed in order to improve the accuracy
of Omega (0) estimates based on cluster number density evolution is a more
reliable measure of the local temperature function and a better understand
ing of the cluster observed properties both in the local Universe and at hi
gh redshift, that is the relation between cluster mass, temperature and lum
inosity. This requires detailed observations of X-ray selected cluster samp
les, in comparison with hydrodynamic simulations including refined physics.