Culture and schizophrenia and other psychotic disorders

Cross-cultural investigations of schizophrenia and other psychotic disorder s have a long tradition of attempting to assess both the universal and cult ural variability of these phenomena. Research in this area received a major boost from the innovative multinational and multicentric studies conducted by the World Health Organization. Results showed that there were certain s imilarities, such as in incidence/prevalence, as well as differences, such as in clinical manifestations, in presentation across cultures. The most st riking difference, however, was the benign course and outcome of schizophre nia in developing countries compared with developed ones. Reasons for this difference are not entirely clear, but it appears that culturally determine d processes are at least partly responsible, thereby meriting further exami nation.