Improved low-energy electron injection systems for high rate electron capture dissociation in Fourier transform ion cyclotron resonance mass spectrometry

Authors
Tsybin, YO Hakansson, P Budnik, BA Haselmann, KF Kjeldsen, F Gorshkov, M Zubarev, RA
Citation
Yo. Tsybin et al., Improved low-energy electron injection systems for high rate electron capture dissociation in Fourier transform ion cyclotron resonance mass spectrometry, RAP C MASS, 15(19), 2001, pp. 1849-1854
Citations number
21
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
ISSN journal
09514198 → ACNP
Volume
15
Issue
19
Year of publication
2001
Pages
1849 - 1854
Database
ISI
SICI code
0951-4198(2001)15:19<1849:ILEISF>2.0.ZU;2-I
Abstract
New low-energy electron injection systems based on indirectly heated dispen ser cathodes facilitate electron capture dissociation (ECD) in Fourier tran sform ion cyclotron resonance (FTICR) mass spectrometry. In this joint repo rt, details are presented of the design and performance of these systems on two commercial FTICR instruments, 9.4 T Bruker BioAPEX in Uppsala and 4.7 T IonSpec Ultima in Odense. New results include obtaining meaningful one-sc an MS/MS data for isolated precursor ions with millisecond irradiation time s. The ECD rate improvement is not only due to the larger total electron cu rrent, but the larger emitting area as well. Copyright (C) 2001 John Wiley & Sons, Ltd.