In this study we evaluated the ability of the transmaxillary route to expos
e the elements of the infratemporal fossa (ITF). Five adult cadaver heads w
ere dissected on both sides, after making a paralateronasal incision. The m
axillary branch of the trigeminal nerve served as a superior landmark to pr
ogress into the retroantral space and pterygopalatine fossa. The maxillary
artery, lateral pterygoid muscle, pterygoid venous plexus, foramen rotundum
and foramen ovale were identified. Distances between those elements and an
gle of approaches of the foramen ovale and foramen rotundum were measured i
n the horizontal plane. In all cases, the anterior loop of the maxillary ar
tery and the sphenopalatine artery were located in the proximal retroantral
fatty space and could be ligated without optic magnification. The maxillar
y nerve could be followed up to the foramen rotundum at a 44 mm mean distan
ce from the opening. The mean angle of vision to the foramen rotundum was 3
1 degrees. Under the greater sphenoid wing and lateral to the pterygoid pro
cess, desinsertion and partial resection of the lateral pterygoid muscle we
re required to identify the pterygoid venous plexus and foramen ovale. The
pterygoid venous plexus was organized as a compact network of channels betw
een and superior to the muscle fibers; it was in close relation with the fo
ramen ovale. Access to the foramen ovale was deep (mean 56 mm) and narrow (
20 degrees). Our results indicate that the transmaxillary approach is a min
imally invasive procedure that gives an appropriate window to the structure
s of the retroantral space and to the pterygomaxillary fissure and pterygop
alatine fossa. Monitoring of the retropterygoid portion of the infratempora
l fossa by this route is inadequate.