An efficient synthesis of 1,4-oxazepines from beta-formyl enamide using I-2-NaHCO3 system

Citation
M. Longchar et al., An efficient synthesis of 1,4-oxazepines from beta-formyl enamide using I-2-NaHCO3 system, SYN COMMUN, 31(21), 2001, pp. 3281-3287
Citations number
32
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
31
Issue
21
Year of publication
2001
Pages
3281 - 3287
Database
ISI
SICI code
0039-7911(2001)31:21<3281:AESO1F>2.0.ZU;2-4
Abstract
A new and efficient method for synthesis of 1,4-oxazepine has been develope d utilizing I-2-NaHCO3 promoted intramolecular cyclisation of N-progargyl-b eta -hydroxylmethyl enamide. The method is mild and simple.