The stereoselective synthesis of N-aryl-trans,trans-alpha-carboxyl-beta-methoxycarbonyl-gamma-aryl-gamma-butyrolactams

Authors
Chen, YL Ding, WY Cao, WG Lu, C
Citation
Yl. Chen et al., The stereoselective synthesis of N-aryl-trans,trans-alpha-carboxyl-beta-methoxycarbonyl-gamma-aryl-gamma-butyrolactams, SYN COMMUN, 31(20), 2001, pp. 3107-3112
Citations number
6
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
31
Issue
20
Year of publication
2001
Pages
3107 - 3112
Database
ISI
SICI code
0039-7911(2001)31:20<3107:TSSON>2.0.ZU;2-2
Abstract
Cis-1-methoxycarbonyl-2-aryl-6,6-dimethyl-5,7-dioxa- spiro[2,5]-4,8-octadio nes (1) in dimethyl ethylene glycol at room temperature react with anilines (2) to give N-aryl-trans, trans-alpha -carboxyl-beta -methoxycarbonyl-gamm a -aryl-gamma -butyrolactams (3) in good to excellent yields and high stere oselectivity.