Assignment of the absolute stereochemistry of oxazinin-1: application of the 9-AMA shift-correlation method for beta-chiral primary alcohols

Authors
Ciminiello, P Dell'Aversano, C Fattorusso, C Fattorusso, E Forino, M Magno, S
Citation
P. Ciminiello et al., Assignment of the absolute stereochemistry of oxazinin-1: application of the 9-AMA shift-correlation method for beta-chiral primary alcohols, TETRAHEDRON, 57(38), 2001, pp. 8189-8192
Citations number
7
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
38
Year of publication
2001
Pages
8189 - 8192
Database
ISI
SICI code
0040-4020(20010917)57:38<8189:AOTASO>2.0.ZU;2-9
Abstract
Reported herein is the assignment of the absolute stereochemistry of oxazin in-1, a cytotoxic compound recently isolated from the digestive glands of M ytilus galloprovincialis of the North Adriatic Sea. The recent 9-AMA shift- correlation method for assigning absolute configuration to beta -chiral pri mary alcohols was employed and preparatory Molecular Mechanics calculations were carried out. (C) 2001 Elsevier Science Ltd. All rights reserved.