Stereocontrolled reduction of an oxazepinohexahydroindolo[2,3-a]quinolizine derivative: asymmetric total synthesis of (+)-tacamonine

Authors
Danieli, B Lesma, G Passarella, D Sacchetti, A Silvani, A
Citation
B. Danieli et al., Stereocontrolled reduction of an oxazepinohexahydroindolo[2,3-a]quinolizine derivative: asymmetric total synthesis of (+)-tacamonine, TETRAHEDR L, 42(41), 2001, pp. 7237-7240
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
41
Year of publication
2001
Pages
7237 - 7240
Database
ISI
SICI code
0040-4039(20011008)42:41<7237:SROAO>2.0.ZU;2-7
Abstract
Efficient, stereocontrolled total synthesis of the title compound is descri bed. starting from enantiopure intermediates. A key step was the diastereos elective catalytic hydrogenation of a pentacyclic oxazepinohexahydroindolo[ 2,3-a]quinolizine derivative. (C) 2001 Elsevier Science Ltd. All rights res erved.