Ca. Sousa et Rew. Halliwell, The ACVD task force on canine atopic dermatitis (XI): the relationship between arthropod hypersensitivity and atopic dermatitis in the dog, VET IMMUNOL, 81(3-4), 2001, pp. 233-237
The relationship between arthropod allergen hypersensitivity and the develo
pment of canine atopic dermatitis (AD) is unclear. It has been shown that d
ogs with AD are more likely to exhibit positive intradermal reactivity to f
lea allergens than non-pruritic dogs from the same flea-endemic a graphic r
egion. Also, dogs in a flea endemic region are four times more likely to su
ffer from flea allergy dermatitis (FAD) and AD than from FAD alone. These r
esults provide indirect evidence to support the hypothesis that, in the can
ine species, atopy predisposes to the development of hypersensitivity to fl
ea allergens and eventually to FAD. A causal relationship between insects o
ther than fleas and canine AD has not been identified with certainty. (C) 2
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