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The concepts of a threshold for pruritus and a threshold for canine atopic
dermatitis (AD) are useful in the understanding of the development of clini
cal manifestations of this disease. Multiple flare factors, such as infecti
ons with bacteria and yeasts, can contribute to the severity of clinical si
gns in affected patients. (C) 2001 Elsevier Science B.V. All rights reserve
d.