Strategy to establish the number of replicates of a medical laboratory test

The allowable error of a test in medical laboratories can be defined by the customer demands based upon the use of the test, or by the appropriate bio logical variation. After correction for systematic bias, the actual analyti cal variation is compared to the stated allowable error. On top of that, pr oper quality control rules should be implemented regarding the number of co ntrol materials and the desired analytical quality assurance as well as ass essment. A strategy is outlined that balances all these factors, taking adv antage of the possibility to diminish the actual analytical variation throu gh the use of replicate tests.