Tripeptide Z-Aib-Aib-Hyp-OMe

Authors
Gessmann, R Bruckner, H Kokkinidis, M
Citation
R. Gessmann et al., Tripeptide Z-Aib-Aib-Hyp-OMe, ACT CRYST E, 57, 2001, pp. o492-o494
Citations number
18
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
ISSN journal
16005368 → ACNP
Volume
57
Year of publication
2001
Part
6
Pages
o492 - o494
Database
ISI
SICI code
1600-5368(200106)57:<o492:TZ>2.0.ZU;2-C
Abstract
The structure of the synthetic protected tripeptide methyl 1-{N-[N-(benzylo xycarbonyl)-alpha -aminoisobutyryl]-alpha -amino-isobutyryl}-4-hydroxypyrro lidine-2-carboxylate (Z-Aib-Aib-Hyp-OMe) ethanol solvate, C22H31N3O7.C2H6O, was determined by X-ray crystallography. The peptide backbone adopts a con formation, which lies in the right-handed helical region for Aib1, in the l eft-handed helical region for Aib2 and in the semi-extended region for Hyp3 .