A series of derivatives of 3-amino-2-oxazolidinone have been prepared. The
5-morpholinomethyl-3-(4-chlorobenzylideneamino)-2-oxazolidinone derivative
is a potential psychotropic drug. Preliminary clinical data showed that the
compound exhibits antidepressive activity in humans. The molecular geometr
y of the title compound, C15H18FN3O3, is similar to 5-morpholinomethyl-3-(4
-chlorobenzylideneamino)-2-oxazol-idinone. Two atoms of the title compound
are disordered so that two different conformations of the oxazolidinone rin
g were found; one is a twist and the other is an envelope conformation. The
crystal structure of title compound is formed by weak intermolecular C-H .
. .O hydrogen bonds resulting in a two-dimensional infinite hydrogen-bond
network.