Citation
N. Nagel et al., Ramipril, ACT CRYST E, 57, 2001, pp. O463-O465
Citations number
17
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
ISSN journal
16005368
→ ACNP
Volume
57
Year of publication
2001
Part
5
Pages
O463 - O465
Database
ISI
SICI code
1600-5368(200105)57:<O463:R>2.0.ZU;2-P
Abstract
The crystal structure of the antihypertensive and cardiovascular protective
ramipril {systematic name: 1-[2-(1-ethoxycarbonyl-3-phenylpropylamino)prop
ionyl]octahydrocyclo-penta[b]pyrrole-2-carboxylic acid}, C23H32N2O5, has be
en determined. Within the crystal structure, strong hydrogen bonds connect
the molecules into chains along the [100] direction. The preferred crystal
growth along these chains causes a crystal morphology of very thin needles
which previously prevented the crystal structure determination.