Variation in breastmilk HIV-1 viral load in left and right breasts during the first 3 months of lactation

Authors
Willumsen, JF Newell, ML Filteau, SM Coutsoudis, A Dwarika, S York, D Tomkins, AM Coovadia, HM
Citation
Jf. Willumsen et al., Variation in breastmilk HIV-1 viral load in left and right breasts during the first 3 months of lactation, AIDS, 15(14), 2001, pp. 1896-1898
Citations number
8
Categorie Soggetti
Immunology
Journal title
AIDS
ISSN journal
02699370 → ACNP
Volume
15
Issue
14
Year of publication
2001
Pages
1896 - 1898
Database
ISI
SICI code
0269-9370(20010928)15:14<1896:VIBHVL>2.0.ZU;2-G
Abstract
The mechanism and risk factors associated with mother-to-child transmission of HIV-1 through breastfeeding remain unclear; breastmilk viral load may b e an important determinant of transmission. Analysis of breastmilk cell-fre e viral load in samples taken from each breast at 1, 6 and 14 weeks postpar tum showed that HIV-1 is shed intermittently and load may differ considerab ly between breasts of an individual woman at any given time. Breastmilk HIV -1 load was undetectable in approximately one-third of samples.