Highly aggressive extraocular sebaceous carcinoma

Extraocular sebaceous carcinoma is an uncommon neoplasm usually localized o n the head and neck. We report a case of sebaceous carcinoma of the axillar y skin with a highly aggressive behavior. The patient was a 43-year-old bla ck man who developed multiple cutaneous and lymph node metastases shortly a fter the excision of primary sebaceous carcinoma of the axillary skin. Many neoplastic aggregations were identified within the lumina of the dermal ly mphatic vessels in the excised specimen of the primary neoplasm. Although e xtraocular sebaceous carcinoma has been traditionally considered a less agg ressive neoplasm than its ocular counterpart, a review of the literature an d this case demonstrate that extraocular sebaceous carcinoma may also lead to disseminated metastatic disease.