Mucoepidermoid carcinoma (MEC) of the thyroid gland is a rare neoplasm with
40 cases reported in the world literature to date. Controversy surrounds t
he treatment of this rare neoplasm. It has been described as a low-grade in
dolent tumor that rarely metastasizes and only recurs locally without morbi
dity. Suggested treatment has consisted of a lobectomy or subtotal thyroide
ctomy. We report a case of a 63-year-old woman with a 15-year history of a
multinodular goiter with a dominant left lobe nodule. Fine-needle aspiratio
n was inconclusive. The patient opted for a total thyroidectomy. Final path
ology yielded a diagnosis of mucoepidermoid carcinoma. We propose that desp
ite its low-grade appearance the morbidity and mortality associated with it
s ability to locally recur and metastasize justify the need for more aggres
sive surgical therapy.