Impairment of human sperm motility and viability by quercetin is independent of lipid peroxidation

Authors
Khanduja, KL Verma, A Bhardwaj, A
Citation
Kl. Khanduja et al., Impairment of human sperm motility and viability by quercetin is independent of lipid peroxidation, ANDROLOGIA, 33(5), 2001, pp. 277-281
Citations number
29
Categorie Soggetti
da verificare
Journal title
ANDROLOGIA
ISSN journal
03034569 → ACNP
Volume
33
Issue
5
Year of publication
2001
Pages
277 - 281
Database
ISI
SICI code
0303-4569(200109)33:5<277:IOHSMA>2.0.ZU;2-E
Abstract
Human sperm motility, viability and lipid peroxidation were assessed in Rin ger-Tyrode supplemented with different concentrations of quercetin. An irre versible and dose-dependent fall in sperm motility was observed with querce tin (5-200 muM). However, sperm viability was decreased only at higher conc entrations (50-100 muM) of quercetin. This inhibition in sperm motility and viability has been linked with decreased Ca2+-ATPase activity, as there wa s no effect of quercetin on sperm lipid peroxidation.