One hundred fifty-one patients with mediastinitis after median sternotomy w
ere treated by a single surgeon over a 6-year period. The infections were a
nalyzed in regard to the depth of infection, time of presentation, and the
mediastinal defect. Preoperative evaluations included computed tomographic
(CT) scans, testing for sternal stability, and the level of contamination.
Intraoperative evaluations included bone, inflammatory tissues, Gram stain,
and cultures. Treatment options included rewire procedures (20 patients),
immediate reconstruction (63 patients), or delayed reconstructions (88 pati
ents). The issues of exposed prosthetic material, right ventricular lacerat
ion, long-term intravenous antibiotics, Candida infections, and reexplorati
on of the healed mediastinum, after flap reconstruction are discussed. The
overall approach to postoperative healing difficulties after sternotomy is
examined. (C) 2001 by The Society of Thoracic Surgeons.