Simple synthesis of climacostol, a defensive secretion by the ciliate Climacostomum virens

Authors
Citation
Y. Abe et K. Mori, Simple synthesis of climacostol, a defensive secretion by the ciliate Climacostomum virens, BIOS BIOT B, 65(9), 2001, pp. 2110-2112
Citations number
5
Categorie Soggetti
Agricultural Chemistry","Biochemistry & Biophysics
Journal title
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
ISSN journal
09168451 → ACNP
Volume
65
Issue
9
Year of publication
2001
Pages
2110 - 2112
Database
ISI
SICI code
0916-8451(200109)65:9<2110:SSOCAD>2.0.ZU;2-I
Abstract
Climacostol {1,3-dihydroxy-5-[(Z)-2'-nonenyl] benzene, 1}, a defensive secr etion by the protozoan ciliate Climacostomum virens against predators, was synthesized in a 43% overall yield in three steps by starting from methyl 1 ,3-bis(tert-butyldimethylsilyloxy) phenylacetate (3).