Hibiscus acid as an inhibitor of starch digestion in the Caco-2 cell modelsystem

Authors
Hansawasdi, C Kawabata, J Kasai, T
Citation
C. Hansawasdi et al., Hibiscus acid as an inhibitor of starch digestion in the Caco-2 cell modelsystem, BIOS BIOT B, 65(9), 2001, pp. 2087-2089
Citations number
18
Categorie Soggetti
Agricultural Chemistry","Biochemistry & Biophysics
Journal title
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
ISSN journal
09168451 → ACNP
Volume
65
Issue
9
Year of publication
2001
Pages
2087 - 2089
Database
ISI
SICI code
0916-8451(200109)65:9<2087:HAAAIO>2.0.ZU;2-Z
Abstract
Hibiscus acid, an alpha -amylase inhibitor isolated from roselle tea, and i ts derivatives were compared in an inhibition test for starch digestion. An alpha -amylase-added Caco-2 system was established as a useful model to ev aluate the effects of alpha -glucosidase inhibitors on starch digestion. Hi biscus acid showed weak inhibition in this model system, and the methyl est er derivatives showed even weaker or no acitivity.