A case of recurring primary hepatic actinomycosis is reported. A 50-year-ol
d man presented with fever, weight loss and multiple hepatic masses. A diag
nosis was obtained by cytological examination of a biopsy sample taken from
the largest hepatic mass, which revealed the presence of Actinomyces speci
es. The patient was treated with penicillin for 12 months and did well. Sev
en years later, he presented with similar symptoms but with a single large
liver mass and a pulmonary infiltrate in the right lower lobe. Liver biopsy
showed an inflammatory pseudotumour, and lung biopsy showed the presence o
f Actinomyces species, Again, the patient was treated with penicillin. Five
months later, the patient was doing well, and a follow-up computed tomogra
phy scan showed partial regression of the hepatic pseudotumour. This case i
ndicates that hepatic actinomycosis can recur several years after an approp
riate treatment and stresses the need for careful follow-up in such patient
s.